Here are five papers on difficulties experienced by adolescents. A couple of the papers are follow-up studies. Colman et al looked at the multiple negative personal & relationship outcomes in a UK national cohort of adolescents with conduct problems followed over 40 years. Wentz et al studied the somewhat more encouraging 18 year outcomes of a group of adolescents suffering from anorexia.
A couple of the papers are about depression. Kennard and colleagues report again on the well-known Treatment for Adolescents with Depression Study (TADS) comparing antidepressants, cognitive-behavioural therapy and combined treatment. By about six months there was little difference between the three forms of treatment. At nine months the remission rate for intent-to-treat cases was 60% overall. Primack et al investigated the association between electronic media use in adolescence and subsequent depression in young adulthood. They reported "Controlling for all covariates including baseline Center for Epidemiologic Studies-Depression Scale score, those reporting more television use had significantly greater odds of developing depression."