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Palmitoylethanolamide (PEA): a well-tolerated dietary supplement with helpful anti-inflammatory & anti-depressive properties

I was intrigued to see the recent paper by Ghazizadeh-Hashemi et al - "Palmitoylethanolamide as adjunctive therapy in major depressive disorder: A double-blind, randomized and placebo-controlled trial" - with its abstract reading: "Experimental studies provide evidence for antidepressant effects of Palmitoylethanolamide (PEA) in animal models of depression.  We aimed to evaluate the efficacy and tolerability of PEA add-on therapy in treatment of patients with major depressive disorder (MDD).  Methods In a randomized double-blind, and placebo-controlled study, 58 patients with MDD (DSM-5) and Hamilton Depression Rating Scale (HAM-D) score ≥ 19 were randomized to receive either 600 mg twice daily Palmitoylethanolamide or placebo in addition to citalopram for six weeks ...

Twelve recent research studies on diet, psychological symptoms & wellbeing (2nd post): magnesium, zinc, folate, fish & selenium

I wrote a post a couple of days ago entitled "Twelve recent research studies on diet, psychological symptoms & wellbeing (1st post): overall dietary quality & depression".  I said that glancing back over recent research studies that I have noticed & downloaded to my personal database, I was struck by a whole series on the effects of diet on psychological state.  I've listed twelve that caught my eye in the last several months - the first post gave half a dozen on overall dietary quality & depression, whereas this post focuses more on specific dietary components.

Twelve recent research studies on diet, psychological symptoms & wellbeing (1st post): overall dietary quality & depression

Glancing back over recent research studies that I have noticed & downloaded to my personal database, I was struck by a whole series on the effects of diet on psychological state.  I've listed twelve that caught my eye in the last several months - this first of two posts details studies that focus more on overall dietary quality.  The second post in the series focuses more on specific dietary components & psychological disorder.  There are obviously lots of interesting developments in this important area.

M: Life skills for stress, health & wellbeing, session 12

I thank you God for most this amazing day: for the leaping greenly spirits of the trees, and a blue true dream of sky; and for everything which is natural which is infinite which is yes.

- e e cummings

Yesterday we had the twelfth & final session of this "Life skills" evening class.  There was scheduled to have been a bit less than a three month gap since the last - eleventh - session.  However the heavy winter snow we'd experienced had resulted in this last session being postponed.

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